个人简介：
教授，博导，山东省泰山学者青年专家，中国分析测试协会智能医学检验分会秘书长、中国医学装备协会骨与软组织修复分会秘书长、中华预防医学会卫生毒理分会委员，中国环境科学学会环境医学与健康分会委员。主要研究气候变化、新污染物等环境因素对造血和免疫系统以及体内代谢的影响和机制，主持国家重点研发计划课题、国自然面上基金等项目，以第一或通讯作者在Blood、Adv Sci、Nano Today、Trends Endocrin Met等主流期刊发表论文多篇。
项目主持情况：
2024-2029，国家重点研发计划“纳米前沿”重点专项课题（2024YFA1210903），储能纳米材料的环境健康风险评估和安全评价预测，422万，主持
2025-2028，国家自然科学基金面上项目（22476115），红细胞介导的微纳塑料体内组织分布及致器官损伤效应，50万，主持
2021-2025，山东省泰山学者青年专家人才称号，50万，主持
2021-2024，国家自然科学基金面上项目（22076104），重金属诱发胎儿红系造血障碍并导致贫血的毒性效应和机制研究，63万，主持
代表论著：
1. Wei Liu#, Yue Wu#, Huaiqing Wei#, Juan Ma, Wenya Feng, Qiuyuan Yang, Shuping Zhang*, Tomas Ganz, Sijin Liu*. Lactate administration improves laboratory parameters in murine models of iron overload. Blood, 2024, 143(11):1045-1049
2. Shuping Zhang, Alejandra Macias-Garcia, Jason Velazquez, Elena Paltrinieri, Randal J. Kaufman, Jane-Jane Chen*. HRI coordinates translation by eIF2aP and mTORC1 to mitigate ineffective erythropoiesis in mice during iron deficiency. Blood, 2018, 131(4):450-461 (封面)
3. Jane-Jane Chen*, Shuping Zhang. Heme-regulated eIF2alpha kinase in erythropoiesis and hemoglobinopthies. Blood, 2019, 134(20):1697-1707
4. Shuping Zhang#, Wei Liu#, Tomas Ganz, Sijin Liu*. Exploring the relationship between hyperlactatemia and anemia. Trends in Endocrinology & Metabolism, 2024, 35(4):300-307
5. Jie Zhang, Chengying Lei, Guangzhe Zheng, Bingxue Nie, Yiju Wei, Yanqin Lu, Shuping Zhang*. CuET promotes cuproptosis and ferroptosis of lung cancer cells by interacting directly with polyunsaturated phospholipids. iScience, 2026, 29(4): 115438
6. Guangzhe Zheng, Jie Zhang, Jin He, Xi Zhou, Huazhong Li, Lingguo Bu, Bingxue Nie, Juan Ma, Xingyi Wang, Sijin Liu, Shuping Zhang*, Yu Qi*, Changwen Zhang*. Lipid peroxidation in macrophages essentially contributes to the development of lung fibrosis. Nano Today, 2025, 61(102612)
7. Guangzhe Zheng#, Shaobo Chen#, Wanqi Ma, Quanshu Wang, Li Sun, Changwen Zhang, Ge Chen, Shuping Zhang*, Shuguang Chen*. Spatial and Single-Cell Transcriptomics Unraveled Spatial Evolution of Papillary Thyroid Cancer. Advanced Science, 2025, 12(2):e2404491
8. Yingying Liu#, Zhiyan Ma#, Xin Wang, Jiaming Liang, Linlin Zhao, Yingyu Zhang, Jiayu Ren, Shuping Zhang*, Yajun Liu*. A Core‐Brush Nanoplatform with Enhanced Lubrication and Anti‐Inflammatory Properties for Osteoarthritis Treatment. Advanced Science, 2024, 11(47):e2406027
9. Lixin Wang, Xuan Zhang, Man Xu, Guangzhe Zheng, Jiamin Chen, Shan Li, Jiansheng Cui, Shuping Zhang*. Implication of ferroptosis in hepatic toxicity upon single or combined exposure to polystyrene microplastics and cadmium. Environmental Pollution, 2023, 334:122250
10. Lixin Wang, Miaomiao Zheng, Yingxue Wang, Lin Yuan, Chengyong Yu, Jiansheng Cui*, Shuping Zhang*. Activation of integrated stress response and disordered iron homeostasis upon combined exposure to cadmium and PCB77. Journal of Hazardous Materials, 2020, 289:121833
